Nilotinib
CAS 641571-10-0
Overview
Nilotinib, sold under the brand name Tasigna, is a medication used to treat chronic myelogenous leukemia which has the Philadelphia chromosome. It may be used both in initial cases of chronic phase CML as well as in accelerated and chronic phase CML that has not responded to imatinib. It is taken by mouth. Cas No:
Anant Labs manufacture and furnish high quality Nilotinib impurities for global markets. Our Nilotinib EP Impurities are used by API manufacturers and fully integrated pharmaceutical companies worldwide.
Technical Data
CAS641571-10-0
Mol. FormulaC28H22F3N7O
Mol. Weight529.526 g/mol
IUPAC4-methyl-N-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]benzamide
SMILESCC1=C(C=C(C=C1)C(=O)NC2=CC(=CC(=C2)C(F)(F)F)N3C=C(N=C3)C)NC4=NC=CC(=N4)C5=CN=CC=C5
InChIInChI=1S/C28H22F3N7O/c1-17-5-6-19(10-25(17)37-27-33-9-7-24(36-27)20-4-3-8-32-14-20)26(39)35-22-11-21(28(29,30)31)12-23(13-22)38-15-18(2)34-16-38/h3-16H,1-2H3,(H,35,39)(H,33,36,37)
InChI KeyHHZIURLSWUIHRB-UHFFFAOYSA-N
Note: We are upgrading our system, Cat No will change.
Synonyms
Nilotinib641571-10-0AMN 107AMN-107nilotinibum4-Methyl-3-((4-(3-pyridinyl)-2-pyrimidinyl)amino)-N-(5-(4-methyl-1H-imidazol-1-yl)-3-(trifluoromethyl)phenyl)benzamideDanzitenNSC-7475994-methyl-N-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]benzamideDTXSID5042663
